Instead, two major approaches will be addressed and those papers that in our belief had the most significance to the development of the field will be described in some detailĪnderson, J. The work on design and analysis for operability in chemical engineering is really vast and a complete review in terms of papers is beyond the scope of this contribution. Although the design-for-operability problem concerns to practically every technical discipline, it has achieved a particular identity within the chemical engineering field due to the economic magnitude of the involved processes. The necessity of integrating design and operability is dictated by the increasing complexity of the processes as result of progressively stringent economic, quality, safety and environmental constraints. Such an interest responds to the fact that the operability quality of a process is determined by design, becoming evident the convenience of considering operability issues in early design stages rather than later when the impact of modifications is less effective and more expensive. In the last decades the chemical engineering scientific research community has largely addressed the design-foroperability problem.
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